amplifier bridge amp ml221 Search Results


ml221  (Bio-Techne corporation)
93
Bio-Techne corporation ml221
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Ml221, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ml221  (MedChemExpress)
94
MedChemExpress ml221
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Ml221, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ml221/product/MedChemExpress
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operational amplifier ml221 bridge amp  (ADInstruments)
90
ADInstruments operational amplifier ml221 bridge amp
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Operational Amplifier Ml221 Bridge Amp, supplied by ADInstruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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operational amplifier ml221 bridge amp - by Bioz Stars, 2026-04
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data recorder ml866p  (POWERLAB INC)
90
POWERLAB INC data recorder ml866p
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Data Recorder Ml866p, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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venous pressure cvp  (ADInstruments)
96
ADInstruments venous pressure cvp
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Venous Pressure Cvp, supplied by ADInstruments, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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continuous arterial pressure monitoring mlt844  (ADInstruments)
90
ADInstruments continuous arterial pressure monitoring mlt844
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Continuous Arterial Pressure Monitoring Mlt844, supplied by ADInstruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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blood pressure amplifiers  (ADInstruments)
97
ADInstruments blood pressure amplifiers
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Blood Pressure Amplifiers, supplied by ADInstruments, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ml221 bridge amplifier  (Harvard Bioscience)
90
Harvard Bioscience ml221 bridge amplifier
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Ml221 Bridge Amplifier, supplied by Harvard Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bridge amplifier 221  (ADInstruments)
90
ADInstruments bridge amplifier 221
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Bridge Amplifier 221, supplied by ADInstruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ml870  (POWERLAB INC)
90
POWERLAB INC ml870
( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor <t>ML221</t> (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.
Ml870, supplied by POWERLAB INC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ml221  (Millipore)
90
Millipore ml221
Effect of apelin on proliferation, migration and invasion abilities of colon cancer cells. ( A ) Proliferation rate of colon cancer cells after apelin peptides (100 nM) stimulation. Results are expressed as the mean (proliferation rate) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( B ) Migration of colon cancer cells after apelin peptides (100 nM) or <t>ML221</t> (100 nM) treatment. Results are expressed as the mean (relative percent of migration) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( C ) Invasion of colon cancer cells after apelin peptides or ML221 treatment. Results are expressed as the mean (relative percent of invasion) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).
Ml221, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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labchart v.7.3.5  (ADInstruments)
90
ADInstruments labchart v.7.3.5
Effect of apelin on proliferation, migration and invasion abilities of colon cancer cells. ( A ) Proliferation rate of colon cancer cells after apelin peptides (100 nM) stimulation. Results are expressed as the mean (proliferation rate) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( B ) Migration of colon cancer cells after apelin peptides (100 nM) or <t>ML221</t> (100 nM) treatment. Results are expressed as the mean (relative percent of migration) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( C ) Invasion of colon cancer cells after apelin peptides or ML221 treatment. Results are expressed as the mean (relative percent of invasion) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).
Labchart V.7.3.5, supplied by ADInstruments, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor ML221 (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.

Journal: Scientific Reports

Article Title: Ontology of the apelinergic system in mouse pancreas during pregnancy and relationship with β-cell mass

doi: 10.1038/s41598-021-94725-0

Figure Lengend Snippet: ( A ) Proliferation of INS1E cells measured by MTT assay in the presence or absence of Apelin (10 nM) or Apela (4 nM) with or without the addition of the Aplnr inhibitor ML221 (10 µM). Values represent mean ± SEM (n = 4–6). *p < 0.05 vs. control, **p < 0.01, ***p < 0.001 vs. Apelin or Apela alone. Cell proliferation of β-cells visualized by fluorescence immunohistochemistry for insulin (green) and Ki67 (red) in islets isolated from neonatal mice incubated without ( B ) or with Apelin (100 nM, C ). Bar represents 50 µm. The percentage of Ki67-positive β-cells was quantified ( D ) in control culture and in the presence of 100 nM or 1 μM apelin. Values represent mean ± SEM (n = 5–6 replicates per experiment). *p < 0.05 vs. control.

Article Snippet: Culture medium contained Apelin (10 nM) or Apela (4 nM) with or without the specific Aplnr antagonist, ML221 (10 µM; BioTechne, Minneapolis, MN, USA).

Techniques: MTT Assay, Fluorescence, Immunohistochemistry, Isolation, Incubation

Effect of apelin on proliferation, migration and invasion abilities of colon cancer cells. ( A ) Proliferation rate of colon cancer cells after apelin peptides (100 nM) stimulation. Results are expressed as the mean (proliferation rate) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( B ) Migration of colon cancer cells after apelin peptides (100 nM) or ML221 (100 nM) treatment. Results are expressed as the mean (relative percent of migration) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( C ) Invasion of colon cancer cells after apelin peptides or ML221 treatment. Results are expressed as the mean (relative percent of invasion) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Journal: Cells

Article Title: Apelin Effects Migration and Invasion Abilities of Colon Cancer Cells

doi: 10.3390/cells7080113

Figure Lengend Snippet: Effect of apelin on proliferation, migration and invasion abilities of colon cancer cells. ( A ) Proliferation rate of colon cancer cells after apelin peptides (100 nM) stimulation. Results are expressed as the mean (proliferation rate) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( B ) Migration of colon cancer cells after apelin peptides (100 nM) or ML221 (100 nM) treatment. Results are expressed as the mean (relative percent of migration) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***); ( C ) Invasion of colon cancer cells after apelin peptides or ML221 treatment. Results are expressed as the mean (relative percent of invasion) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Article Snippet: [Pyr1] apelin-13 (pQRPRLSHKGPMPF), apelin-13 (QRPRLSHKGPMPF), -17 (KFRRQRPRLSHKGPMPF) and -36 (LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF) were from Bachem (Bubendorf, Switzerland), and ML221 was from Sigma.

Techniques: Migration

Influence of apelin on blebs formation. ( A ) Representative localization of ezrin (green), filamentous actin (red) and nuclei (blue) in colon cancer cells after apelin peptides (100 nM) or ML221 (100 nM) stimulation. Arrowheads indicate migratory protrusions. Scale bars represent 10 μm; ( B ) Quantification of the number of cells forming blebs after apelin peptides or ML221 treatment, shown as a percent of control cells. Results are expressed as the mean (cells forming blebs) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***). Representative Western blot; ( C ) and densitometric ( D ) analysis for level of ezrin in tested cells incubated with apelin peptides or ML221. The GAPDH level was shown as a loading control. Results are expressed as the mean ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Journal: Cells

Article Title: Apelin Effects Migration and Invasion Abilities of Colon Cancer Cells

doi: 10.3390/cells7080113

Figure Lengend Snippet: Influence of apelin on blebs formation. ( A ) Representative localization of ezrin (green), filamentous actin (red) and nuclei (blue) in colon cancer cells after apelin peptides (100 nM) or ML221 (100 nM) stimulation. Arrowheads indicate migratory protrusions. Scale bars represent 10 μm; ( B ) Quantification of the number of cells forming blebs after apelin peptides or ML221 treatment, shown as a percent of control cells. Results are expressed as the mean (cells forming blebs) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***). Representative Western blot; ( C ) and densitometric ( D ) analysis for level of ezrin in tested cells incubated with apelin peptides or ML221. The GAPDH level was shown as a loading control. Results are expressed as the mean ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Article Snippet: [Pyr1] apelin-13 (pQRPRLSHKGPMPF), apelin-13 (QRPRLSHKGPMPF), -17 (KFRRQRPRLSHKGPMPF) and -36 (LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF) were from Bachem (Bubendorf, Switzerland), and ML221 was from Sigma.

Techniques: Western Blot, Incubation

Effect of apelin on actin polymerisation and level of cofilin. ( A ) Ratio of F-actin to G-actin in colon cancer cells after apelin peptides (100 nM) or ML221 (100 nM) treatment. Results are expressed as the mean (F:G ratio) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***). Representative Western blot ( B ) and densitometric ( C ) analysis of levels of cofilin in tested cells incubated with apelin peptides or ML221. The GAPDH level is shown as a loading control. Results are expressed as the mean ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Journal: Cells

Article Title: Apelin Effects Migration and Invasion Abilities of Colon Cancer Cells

doi: 10.3390/cells7080113

Figure Lengend Snippet: Effect of apelin on actin polymerisation and level of cofilin. ( A ) Ratio of F-actin to G-actin in colon cancer cells after apelin peptides (100 nM) or ML221 (100 nM) treatment. Results are expressed as the mean (F:G ratio) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***). Representative Western blot ( B ) and densitometric ( C ) analysis of levels of cofilin in tested cells incubated with apelin peptides or ML221. The GAPDH level is shown as a loading control. Results are expressed as the mean ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Article Snippet: [Pyr1] apelin-13 (pQRPRLSHKGPMPF), apelin-13 (QRPRLSHKGPMPF), -17 (KFRRQRPRLSHKGPMPF) and -36 (LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF) were from Bachem (Bubendorf, Switzerland), and ML221 was from Sigma.

Techniques: Western Blot, Incubation

Influence of apelin on proteolytic activity of colon cancer cells. ( A ) The proteolytic activity of colon cancer cells (red) after apelin peptides (100 nM) or ML221 (100 nM) stimulation using FITC-conjugated gelatine (green). Scale bars represent 10 μm; ( B ) The number of cells digesting gelatine was expressed as a percent of digesting cells and results are shown as a percent of control. Results are expressed as the mean (percent of digesting cells) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Journal: Cells

Article Title: Apelin Effects Migration and Invasion Abilities of Colon Cancer Cells

doi: 10.3390/cells7080113

Figure Lengend Snippet: Influence of apelin on proteolytic activity of colon cancer cells. ( A ) The proteolytic activity of colon cancer cells (red) after apelin peptides (100 nM) or ML221 (100 nM) stimulation using FITC-conjugated gelatine (green). Scale bars represent 10 μm; ( B ) The number of cells digesting gelatine was expressed as a percent of digesting cells and results are shown as a percent of control. Results are expressed as the mean (percent of digesting cells) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**), p ≤ 0.001 (***).

Article Snippet: [Pyr1] apelin-13 (pQRPRLSHKGPMPF), apelin-13 (QRPRLSHKGPMPF), -17 (KFRRQRPRLSHKGPMPF) and -36 (LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF) were from Bachem (Bubendorf, Switzerland), and ML221 was from Sigma.

Techniques: Activity Assay

Effect of apelin on the level of MT1-MMP in colon cancer cells. ( A ) The localization of MT1-MMP (black) in tested cells treated with apelin peptides (100 nM) or ML221 (100 nM). Scale bars represent 10 μm; ( B ) Quantification of the number of MT1-MMP positive signals after apelin peptides or ML221 treatment showed as a percent of control cells. Results are expressed as the mean (number of MT1-MMP positive signals) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**).

Journal: Cells

Article Title: Apelin Effects Migration and Invasion Abilities of Colon Cancer Cells

doi: 10.3390/cells7080113

Figure Lengend Snippet: Effect of apelin on the level of MT1-MMP in colon cancer cells. ( A ) The localization of MT1-MMP (black) in tested cells treated with apelin peptides (100 nM) or ML221 (100 nM). Scale bars represent 10 μm; ( B ) Quantification of the number of MT1-MMP positive signals after apelin peptides or ML221 treatment showed as a percent of control cells. Results are expressed as the mean (number of MT1-MMP positive signals) ± SD of three independent experiments. p ≤ 0.05 (*), p ≤ 0.01 (**).

Article Snippet: [Pyr1] apelin-13 (pQRPRLSHKGPMPF), apelin-13 (QRPRLSHKGPMPF), -17 (KFRRQRPRLSHKGPMPF) and -36 (LVQPRGSRNGPGPWQGGRRKFRRQRPRLSHKGPMPF) were from Bachem (Bubendorf, Switzerland), and ML221 was from Sigma.

Techniques: